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Ascorbic acid in the prevention of chromium dermatitis
Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
|January 1, 1980
Summary
A novel topical ascorbic acid treatment effectively managed chromium-induced hand dermatitis in a worker. This method allowed for continued employment by reducing toxic hexavalent chromium exposure.
Area of Science:
- Occupational Health
- Dermatology
- Toxicology
Background:
- A worker experienced severe hand dermatitis due to occupational exposure to hexavalent chromium in printing inks.
- Standard treatments like gloves, barrier creams, oral antihistamines, and corticosteroids were not viable options for this employee.
Observation:
- The worker's essential role necessitated a practical solution to manage his chromium sensitivity without disrupting his work.
- Conventional protective measures and systemic treatments were deemed unsuitable for the specific work environment and employee needs.
Findings:
- A 10% ascorbic acid solution applied topically to the hands successfully reduced active hexavalent chromium to its inactive trivalent form.
- This intervention led to rapid symptom resolution and recovery from severe hand dermatitis.
Implications:
- Topical ascorbic acid presents a cost-effective and simple method for managing occupational chromium exposure and dermatitis.
- The successful application demonstrates a potential strategy for retaining valuable employees facing similar chemical sensitivities in the workplace.