Related Experiment Video
Updated: Aug 4, 2026
08:21
Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries
Published on: April 1, 2019
Vertebral North American blastomycosis
Surgical Neurology
|April 1, 1980
Summary
A rare case of back pain caused by Blastomyces dermatitidis bone infection is presented. Prompt diagnosis is crucial to differentiate this fungal infection from other bone lesions for effective treatment.
Area of Science:
- Mycology
- Infectious Diseases
- Orthopedics
Background:
- Blastomyces dermatitidis is a fungus endemic to North America.
- Osteoarticular involvement is a rare manifestation of blastomycosis.
- Skeletal infections require differentiation from other bone pathologies.
Observation:
- A single case of back pain attributed to Blastomyces dermatitidis infection exclusively affecting the skeleton is detailed.
- The clinical presentation mimicked other destructive bone lesions.
Findings:
- The case highlights the importance of considering fungal infections in the differential diagnosis of bone pain.
- Blastomyces dermatitidis can cause isolated skeletal lesions.
Implications:
- Early and accurate diagnosis of skeletal blastomycosis is essential.
- Distinguishing fungal osteomyelitis from tuberculosis or neoplastic lesions ensures appropriate and timely therapeutic intervention.
- This case underscores the need for increased awareness of rare fungal infections in orthopedic settings.
Related Concept Videos
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:18Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
01:25Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
01:27Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...