Eosinophilic granulomas of the lung. Histopathology of three cases

Three cases of eosinophilic granuloma of the lung were histopathologically analyzed on surgical materials (two resections and lung biopsy). The analysis insisted upon the cell components of pulmonary lesions, histiocytic and eosinocytic accumulations involving lobular air spaces, alveolar walls and interlobular areas, and forming bullae by histiocytic enzymic activity and lipid dysmetabolism; the fibrotic evolution of the lesions varied from case to case. The lesional histogenesis is discussed in the light of recent electronmicroscropic, histochemical and immunopathological data, stress being laid upon the local influence on the development of the process.