Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical evaluation of piperacillin.

H Thadepalli, B Rao, D White

    Chemotherapy
    |January 1, 1980
    PubMed
    Summary

    Intravenous piperacillin effectively treated aerobic, anaerobic, and mixed bacterial infections in 28 patients. This study found piperacillin safe and effective for clinical infections, with a 93% cure rate.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Investigating the diagnostic accuracy of GPT-4's novel image analytics feature in dermatology.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2024
    Same author

    Imaging and Staging of Endometrial Cancer.

    Seminars in ultrasound, CT, and MR·2019
    Same author

    Ischiorectal fossa: benign and malignant neoplasms of this "ignored" radiological anatomical space.

    Abdominal radiology (New York)·2019
    Same author

    Regarding "MR Imaging of the Cervical Spine in Nonaccidental Trauma: A Tertiary Institution Experience".

    AJNR. American journal of neuroradiology·2017
    Same author

    Fast island phase identification for tearing mode feedback control on J-TEXT tokamak.

    The Review of scientific instruments·2016
    Same author

    Use of Everolimus After Multivisceral Transplantation: A Report of Two Cases.

    Transplantation proceedings·2016

    Area of Science:

    • Infectious Diseases
    • Pharmacology
    • Clinical Microbiology

    Background:

    • Bacterial infections pose a significant clinical challenge.
    • Effective antibiotic therapy is crucial for patient outcomes.
    • Piperacillin is a broad-spectrum penicillin antibiotic.

    Purpose of the Study:

    • To evaluate the safety and efficacy of intravenous piperacillin in treating various bacterial infections.
    • To assess treatment outcomes and adverse effects in patients receiving piperacillin.

    Main Methods:

    • A cohort of 28 patients with aerobic, anaerobic, and mixed infections received intravenous piperacillin.
    • Dosage adjusted for renal function; some patients received additional gentamicin for Staphylococcus aureus infections.
    • Bacterial susceptibility to piperacillin was confirmed; serum levels were monitored.

    Main Results:

    • 26 out of 28 patients (93%) achieved a 'cured' status.
    • One patient experienced recurrence, and one patient had treatment failure.
    • Adverse effects were mild and transient, including pruritus, elevated LDH, and eosinophilia.

    Conclusions:

    • Intravenous piperacillin demonstrated safety and efficacy in treating a range of bacterial infections.
    • Piperacillin is a viable treatment option for aerobic, anaerobic, and mixed bacterial infections.
    • Further investigation may be warranted based on these preliminary findings.

    Related Experiment Videos