[Patholphysiological aspects of hyperbaric oxygenation exposure on the heart in compensatory hypertrophy]

Chronic interrupted effect of hyperbaric oxygenation applied for 4 weeks reduces the rate of the development of myocardial hypertrophy in rabbits and is thus conducive to stabilization of myocardial contractile function on a sufficiently high level and increases the reliability of the circulation system in emergency situations. In the dangerous stage of compensatory cardiac hyperfunctions, hyperbaric oxygenation protects the myocardium from destructive changes and activates bionergetic processes, whereas in the stage of marked hypertrophy it inhibits the development of cardiosclerosis. Hyperbaric oxygenation prevents the development of functional isolation of the hypertrophied myocardium from the neurohormonal effects and contributes to the preservation of the reserve capacity of the neuroeffector mechanisms of heart regulations.