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Induction of suppressor cells in mice following Vaccinia virus infection
Medical Microbiology and Immunology
|January 1, 1980
Abstract:
Infection of mice with Vaccinia virus produced suppression of responsiveness of spleen cells to mitogens in vitro and suppression of delayed-type hypersensitivity in vivo. The latter suppression was transferred to normal mice by spleen cells of virus-infected mice. The data presented show that Vaccinia virus-induced immunosuppression involves the induction of suppressor cells which belong to both the adherent and non-adherent cell fractions.