[Age-dependent immunological parameters]

Immunitat Und Infektion
|January 1, 1980
PubMed

Lymphocyte stimulation, frequency of autoantibodies and concentration of immunoglobuline classes were investigated in 90 persons of 3 age-groups (5--15, 30--40 and 65--95 years of age). An age dependent decrease of MLC- and PhA-reactivity was observed. In contrast, the frequency of autoantibodies and the concentration of IgA increased with age. Individuals with a positive antinuclear factor demonstrated decreased IgA levels. No correlation between lymphocyte stimulation and autoantibody-frequency could be observed.

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