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Updated: Aug 14, 2026

Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
Published on: April 16, 2012
[Age-dependent immunological parameters]
Lymphocyte stimulation, frequency of autoantibodies and concentration of immunoglobuline classes were investigated in 90 persons of 3 age-groups (5--15, 30--40 and 65--95 years of age). An age dependent decrease of MLC- and PhA-reactivity was observed. In contrast, the frequency of autoantibodies and the concentration of IgA increased with age. Individuals with a positive antinuclear factor demonstrated decreased IgA levels. No correlation between lymphocyte stimulation and autoantibody-frequency could be observed.
Lymphocyte stimulation, frequency of autoantibodies and concentration of immunoglobuline classes were investigated in 90 persons of 3 age-groups (5--15, 30--40 and 65--95 years of age). An age dependent decrease of MLC- and PhA-reactivity was observed. In contrast, the frequency of autoantibodies and the concentration of IgA increased with age. Individuals with a positive antinuclear factor demonstrated decreased IgA levels. No correlation between lymphocyte stimulation and autoantibody-frequency could be observed.
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