Changes in sarcomere length following tenotomy in the rat

The medial belly of the gastrocnemius and the extensor digitorum longus muscles of rats were tenotomized. One day following tenotomy, the mean sarcomere length of the fast medial gastrocnemius was 1.8 microns, a value comparable to that of tenotomized slow soleus. The mean sarcomere length of the tenotomized extensor digitorum longus, however, was 2.0 microns, a figure which differed significantly from the values obtained for both the soleus and the gastrocnemius. Histological preparations showed the presence of central core degeneration in slow fatigue-resistant fibers of the tenotomized gastrocnemius comparable to that seen in the soleus. No changes were found in the fibers of the tenotomized extensor digitorum longus. The fact that central core lesions were produced in the fibers of soleus and medial gastrocnemius but not in the extensor digitorum longus may be related to the lesser reduction in sarcomere length following tenotomy of the latter muscle.