[Gold therapy in chronic polyarthritis. Differentiation of allergic and toxic side effects]

The data from 310 patients treated with gold were analysed. The occurrence of side effects is lower than the average data in the literature: with "Solganal" 21.5%, with "Tauredon" 21%. The clinical importance of the differentiation of toxic and allergic side effects is pointed out. It seems possible to differentiate between the toxic-allergic and the dosage dependent, actually toxic side effects. In cases of toxicity caused by retarded metabolisation the use of the barbiturate enzyme induction made it possible to continue treatment.