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Updated: Aug 8, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
Alcoholism, depression, and life events
Abstract:
Alcoholics with and without secondary depression were compared on a wide variety of clinical variables. Subjects with secondary depression reported more fights, arrests, neurotic complaints, suicidal behavior, and recent undesirable life events than subjects with alcoholism alone. The data indicate a close relationship between negative events and the secondary depression of alcoholism. In addition, the findings suggest that the alcoholic with secondary depression is at greater risk for suicide than the alcoholic without a depressive syndrome.
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