[Interactions of cytosol enzymes with the red blood cell membrane]

It is not dubious that the regulation of erythrocyte metabolism occurs across the membrane and that accordingly interactions between cytosolic enzymes and membrane components necessarily exist. Several aspects of such relationships were reviewed. The results of some experiments carried out in non-physiological conditions should be carefully interpreted. However it can be accepted that some enzymes undergo reciprocal translocations between cytosol and membrane and that very probably these transfers play a role in the control of metabolic regulation in the red cell.