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[The myocardfunction in chronic obstructive lung diseases with different pathogenesis (author's transl)].

W Schilling

    Zeitschrift Fur Erkrankungen Der Atmungsorgane
    |May 1, 1980
    PubMed
    Summary

    Patients with chronic obstructive lung diseases (COPD) show varying myocardial function. Type B and M patients exhibit higher cardiac load, while Type A patients have limited exercise capacity and increased risk of heart failure.

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    Area of Science:

    • Cardiology
    • Pulmonology
    • Exercise Physiology

    Background:

    • Chronic obstructive lung diseases (COPD) significantly impact systemic health, including cardiovascular function.
    • Myocardial function, encompassing contractility, hypertrophy, and reagibility, is crucial for assessing patient outcomes.
    • Classifying COPD patients into specific phenotypes (Type A, B, M) may reveal distinct physiological responses.

    Purpose of the Study:

    • To investigate and compare myocardial function in different COPD patient phenotypes (Type A, B, M).
    • To assess contractility, hypertrophy, and reagibility under defined ergometric conditions.
    • To identify potential risks for cardiac insufficiency based on COPD type and exercise response.

    Main Methods:

    • Patient stratification into three groups: Type A (pink puffer), Type B (blue bloater), and Type M (mixed), based on Dornhorst and Nash criteria.

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  • Evaluation of myocardial function, including contractility, hypertrophy, and reagibility.
  • Assessment under specific ergometric (exercise testing) conditions.

    • Main Results:

    • Significant differences in contractility and hypertrophy were observed among the COPD patient groups.
    • Type B and Type M patients demonstrated the highest cardiac load concerning hypertrophy and contractility.
    • Type A patients exhibited a limited functional reserve and poorer adaptation to exercise, indicating a higher risk of cardiac insufficiency.

    Conclusions:

    • COPD phenotype significantly influences myocardial function and exercise tolerance.
    • Type B and M COPD patients experience a greater cardiac burden compared to Type A.
    • Type A patients are at elevated risk for developing cardiac insufficiency due to impaired exercise adaptation.