[Diffuse skeletal hemangiomatosis with involvement of internal organs (author's transl)]

Generalized haemangiomatosis of the skeletal is a very rare disease without characteristic radiological symptoms. The authors, who observed one case, give a survey of the literature, radiologic symptoms, pathological changes, clinical and therapeutical problems as well as of the prognosis. Stress is layed on the fact, that there is a marked distinction between generalized haemangiomatosis and progressive osteolysis Gorham-Stout. Attempts are made to find reliable characteristics for differentiation of a variety of pathological conditions, which present similar radiological pattern. The presented case shows uncommon osteoblastic bone changes, symptoms, which are rarely observed in this condition. The prognosis depends on the involvement of parenchymal organs: The nature of the disease should be judged as semimalign in cases of simultaneous involvement of skeletal and inner organs due to the high mortality, even in a definite benign histology.