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[Experience in treating vascular parkinsonism with metamysil]
Abstract:
The paper is concerned with a study of the effect of metamizil in 45 patients with different forms of vascular parkinsonism. It was established that metamizil exerts a positive effect on the development of neurological symptoms (rigidity, bradykinesia, tremor) in mild and moderately expressed degrees of lesions. In most of the cases the drugs appeared effective in doses of 0.001 g thrice daily, and in separate cases 0.001 g 6 times daily. In the majority of patients metazil was tolerated without significant side effects. In some patients the side effects (vertigo, dryness in the mouth) were slightly expressed. The effect of treatment was seen after 2 days up to 2 weeks and lasted during the whole course of treatment and sometimes after it. Metamizil possessing a moderate sedative action, as well as spasmolytical and hypotensive is indicated for patients with vascular parkinsonism.
Insights
Metamizil effectively improved neurological symptoms like rigidity and tremor in vascular parkinsonism patients. This medication was well-tolerated, showing positive effects within two weeks.
Area of Science:
- Neurology
- Pharmacology
Background:
- Vascular parkinsonism is a neurological disorder affecting movement.
- Treatment options for vascular parkinsonism symptoms are limited.
Purpose of the Study:
- To evaluate the efficacy and safety of metamizil in patients with vascular parkinsonism.
Main Methods:
- A study involving 45 patients with various forms of vascular parkinsonism.
- Assessment of neurological symptoms including rigidity, bradykinesia, and tremor.
- Dosage evaluated: 0.001 g thrice daily, and in some cases, 0.001 g six times daily.
Main Results:
- Metamizil demonstrated a positive effect on neurological symptoms in mild to moderate cases.
- Treatment effects were observed within 2 days to 2 weeks and persisted.
- The drug was generally well-tolerated, with mild side effects like vertigo and dry mouth reported in some patients.
Conclusions:
- Metamizil is indicated for vascular parkinsonism due to its efficacy in improving motor symptoms.
- Its sedative, spasmolytic, and hypotensive properties contribute to its therapeutic value.
- Metamizil offers a potentially beneficial treatment option with a favorable safety profile for this condition.