Acute renal failure due to seminoma metastatic to the kidneys

A patient with seminoma presenting with bilateral symmetrical enlargement of the kidneys, massive proteinuria and acute renal failure is described. No factor other than infiltration due to seminoma was found to explain the renal failure. Renal function improved markedly along with renal size and architecture in response to radiotherapy. Renal dialysis is justified in metastatic seminoma to determine the effect of tumor therapy.