Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Propranolol rebound--a retrospective study.

R A Shiroff, J Mathis, R Zelis

    The American Journal of Cardiology
    |April 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Interstitial Granulomatous Drug Reaction to Ustekinumab.

    Case reports in dermatological medicine·2022
    Same author

    Can we use robotic surgery for the treatment of pelvic recurrence and locally advanced tumors in gynecological surgery?

    Journal of gynecology obstetrics and human reproduction·2018
    Same author

    Do optic nerve head and visual field parameters in patients with obstructive sleep apnea syndrome differ from those in control individuals?

    Klinische Monatsblatter fur Augenheilkunde·2014
    Same author

    Sleepiness and vigilance tests.

    Swiss medical weekly·2009
    Same author

    Isolated mediotegmental lesion causing narcolepsy and rapid eye movement sleep behaviour disorder: a case evidencing a common pathway in narcolepsy and rapid eye movement sleep behaviour disorder.

    Journal of neurology, neurosurgery, and psychiatry·2007
    Same author

    Sleep-wake disturbances in sporadic Creutzfeldt-Jakob disease.

    Neurology·2006
    Same journal

    Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

    The American journal of cardiology·2026
    Same journal

    ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

    The American journal of cardiology·2026
    Same journal

    Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

    The American journal of cardiology·2026
    Same journal

    Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

    The American journal of cardiology·2026
    Same journal

    Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

    The American journal of cardiology·2026
    Same journal

    Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

    The American journal of cardiology·2026
    See all related articles

    Sudden withdrawal of propranolol in cardiac patients undergoing catheterization showed infrequent rebound effects. This suggests reduced risk for coronary artery disease patients with decreased activity levels.

    Area of Science:

    • Cardiology
    • Pharmacology

    Background:

    • Propranolol is a beta-blocker commonly prescribed for coronary artery disease (CAD).
    • Sudden withdrawal of beta-blockers can potentially lead to rebound effects, including cardiovascular events.

    Purpose of the Study:

    • To evaluate the incidence of propranolol withdrawal syndrome in hospitalized patients with coronary artery disease (CAD).
    • To assess the safety of abrupt propranolol discontinuation prior to cardiac catheterization.

    Main Methods:

    • A study involving 102 inpatients with angiographically confirmed CAD was conducted.
    • Patients were divided into two groups: one group abruptly discontinued propranolol (n=55), and a control group continued propranolol therapy (n=47).
    • Morbidity outcomes included death, myocardial infarction, and changes in pain patterns.

    Related Experiment Videos

    Main Results:

    • No deaths were reported in the propranolol withdrawal group.
    • One myocardial infarction occurred, deemed related to the catheterization procedure, not propranolol withdrawal.
    • Only one patient in the withdrawal group experienced a change in pain pattern.

    Conclusions:

    • Propranolol rebound appears to be infrequent in hospitalized coronary artery disease patients with reduced activity.
    • Abrupt discontinuation of propranolol may be safe in this specific patient population prior to cardiac catheterization.