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Visualization of MG53-mediated Cell Membrane Repair Using in vivo and in vitro Systems
Published on: June 30, 2011
Enzyme reactions in beige mouse muscle with central cores
Abstract:
In this paper enzyme activities in cylindric structures from striated muscle fibers of the beige mutant mouse are described. While most of the sarcoplasm possesses a reaction for myosin and sarcoplasmic reticular ATPase, succinic dehydrogenase, and lactic dehydrogenase similar to that described for normal non-mutant mice, the cylinders are totally free from activity of these enzymes. The staining pattern thus resembles earlier reports of the central core disease in humans and suggests that the beige mouse is a suitable animal model for this myopathy.
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