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[Extracranial arterial occlusive disease in arteriopathies with peripheral vascular disease (author's transl)]
Insights
Patients with peripheral arterial occlusive disease often have blockages in neck arteries like the carotid and vertebral arteries. The severity of these arterial blockages correlates with clinical symptoms and disease extent.
Area of Science:
- Vascular Surgery
- Radiology
- Cardiology
Background:
- Peripheral arterial occlusive disease (PAOD) is a common condition affecting arteries outside the heart and brain.
- Supraaortic vessel involvement is a significant concern in patients with PAOD.
- Understanding the extent and correlation of arterial disease is crucial for patient management.
Purpose of the Study:
- To investigate the prevalence of supraaortic vessel stenoses or occlusions in patients with peripheral arterial occlusive disease.
- To correlate the angiographic findings of supraaortic and lower extremity arterial disease with clinical severity.
- To assess the risk of extracranial arterial occlusion based on the extent of arteriosclerosis.
Main Methods:
- Aortography and angiography of the aortic arch were performed in 176 patients.
- Hemodynamic relevance of stenoses or occlusions in supraaortic and peripheral arteries was assessed.
- Correlation analysis was conducted between angiographic findings and clinical severity (cerebrovascular insufficiency and Fontaine stages).
Main Results:
- 63.6% of patients had hemodynamically relevant stenoses/occlusions of supraaortic vessels, most commonly carotid (39.2%) and vertebral arteries (35.2%).
- Peripheral arterial disease involved femoro-popliteal arteries (83%), aorto-iliac arteries (67.1%), and calf vessels (58.5%).
- A significant correlation was found between clinical severity and angiographic extent of arteriosclerosis, with increased risk of extracranial arterial occlusion in multi-level disease.
Conclusions:
- Supraaortic vessel disease is highly prevalent in patients with peripheral arterial occlusive disease.
- The extent of arteriosclerosis in peripheral arteries correlates significantly with cerebrovascular insufficiency and clinical Fontaine stages.
- Multi-level arterial involvement increases the risk of extracranial arterial occlusion.
Abstract:
Aortography and angiography of the aortic arch were carried out in 176 patients with peripheral arterial occlusive disease. In 63,6% there were haemodynamically relevant stenoses or occlusions of the supraaortic vessels, the carotid arteries with 39,2% and the vertebral arteries with 35,2%, being the most commonly involved. Peripheral arterial disease included haemodynamically relevant changes in the femoro-popliteal arteries in 83%, in the aorto-iliac region in 67,1% and in the calf vessels in 58,5%. There was a statistically significant correlation between the clinical severity of the cerebrovascular insufficiency and of the Frontaine stages with the angiographically demonstrable extent of the arteriosclerosis. In addition there was an increasing statistical risk of extracranial arterial occlusion if the disease affected more than one arterial level.