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Metoclopramide in double contrast barium meal
Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|November 1, 1980
Summary
Metoclopramide did not significantly improve gastric mucosal coating during double contrast barium meals. This study found no benefit in using metoclopramide for enhancing visualization of the gastric mucosal coating.
Area of Science:
- Gastroenterology
- Radiology
- Pharmacology
Background:
- A high-quality gastric mucosal coating is crucial for accurate double contrast barium meal examinations.
- Metoclopramide is a prokinetic agent sometimes used to improve gastrointestinal examinations, but its effect on mucosal coating is unclear.
Purpose of the Study:
- To investigate the effect of metoclopramide on the visibility of gastric mucosal coating during double contrast barium meal examinations.
- To determine if metoclopramide enhances the quality of mucosal coating as indicated by the visibility of the areae gastricae.
Main Methods:
- A randomized, double-blind, placebo-controlled study was conducted.
- 130 patients undergoing double contrast barium meal were randomly assigned to receive either 20 mg metoclopramide or a placebo prior to the procedure.
- The visibility of the areae gastricae served as the primary outcome measure for mucosal coating quality.
Main Results:
- Metoclopramide administration did not result in a statistically significant difference in the visibility of the areae gastricae compared to placebo.
- The study found no significant improvement in gastric mucosal coating quality with the use of metoclopramide.
Conclusions:
- Metoclopramide does not appear to have a beneficial effect on gastric mucosal coating in the context of double contrast barium meal examinations.
- Routine use of metoclopramide for enhancing mucosal coating in this specific radiological procedure is not supported by these findings.