[Use of naloxone (Narcar) in anesthesiological practice]

The antagonising effect induced on respiratory depression by fentanyl and morphine was studied in two lots of patients. Recovery from respiratory depression was general and evident. A correlation was found between the amount of naloxone and the amount of the major analgesic used. Beside respiratory depression naloxone has also partially antagonised in some cases the analgesic effects of fentanyl and morphine.