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Heart weights among octogenarians.

Journal of the American Geriatrics Society

|December 1, 1981

Summary

This summary is machine-generated.

Heart weights in octogenarians are significantly higher than average, with many showing age-related cardiac changes. These findings suggest heavy hearts are common in advanced age groups.

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Area of Science:

Gerontology
Cardiovascular Pathology

Background:

Advanced age is associated with various physiological changes, including potential alterations in cardiac structure and function.
Understanding age-related changes in heart weight is crucial for interpreting cardiovascular health in elderly populations.

Purpose of the Study:

To investigate the heart weights and associated pathological findings in a cohort of octogenarians.
To compare heart weights in octogenarians with a previous study on nonagenarians.

Main Methods:

Autopsy examination of 110 octogenarian subjects.
Measurement of heart weights and documentation of macroscopic cardiac abnormalities.
Comparison of findings with a prior study of 39 nonagenarians.

Main Results:

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Heart weights in octogenarians ranged from 174 to 785 gm, exceeding typical adult norms.
Only 15% of subjects had hearts considered normal; common findings included hypertrophy, friable muscle, fatty infiltration, brown atrophy, flabby myocardium, valvular changes, and coronary atheroma/calcification.
Octogenarian heart weights were generally higher than those observed in nonagenarians (159-539 gm).

Conclusions:

Elevated heart weights are prevalent in octogenarians and nonagenarians.
Numerous pathological cardiac changes are frequently observed in the elderly, often correlating with increased heart weight.