Effect of alpha-difluoromethylornithine on cardiac polyamine content and hypertrophy

A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome.

American journal of medical genetics. Part A·2009

New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome.

Journal of medical genetics·2008

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.

Amino acids·2007

Polyamines and neoplastic growth.

Biochemical Society transactions·2007

Polyamine depletion inhibits etoposide-induced NF-kappaB activation in transformed mouse fibroblasts.

Amino acids·2004

Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth.

Biochemical Society transactions·2003

Graft IL-33/ST2 signaling promotes cardiac allograft vasculopathy by modulating cardiac resident cell function.

Journal of molecular and cellular cardiology·2026

Mitofusin 2 deficiency causes atrial lipid accumulation in experimental and human atrial fibrillation and diabetes mellitus.

Journal of molecular and cellular cardiology·2026

PP2A promotes myocardial regeneration through YAP.

Journal of molecular and cellular cardiology·2026

Pharmacological modulation of GLI signaling promotes human iPSC-derived cardiomyocyte maturation via PGC1α-associated mitochondrial programs.

Journal of molecular and cellular cardiology·2026

Whole-genome sequencing identifies a c.1282C > T missense variant in Taurine Transporter (TauT) associated with taurine-mediated dilated cardiomyopathy in a family of domestic shorthair cats.

Journal of molecular and cellular cardiology·2026

Icosapent ethyl activates GPR120 to improve post-myocardial infarction cardiac remodeling by suppressing CXCR3+ inflammatory cells.

Journal of molecular and cellular cardiology·2026

Enzyme replacement therapy (ERT) combined with transient low-dose methotrexate (TLD-MTX) results in age- and disease-dependent immune profile changes in Infantile- vs. late-onset Pompe disease patients.

Frontiers in immunology·2026

Mitochondria-Targeted Nanozyme Reprograms Dendritic-Cell Immunometabolism via Microenvironment-Responsive CO Release to Treat Periodontitis.

Advanced healthcare materials·2026

Microaneurysm segmentation in early diabetic retinopathy: a localized patch-based U-Net approach to overcome microscopic lesion oversight.

International journal of retina and vitreous·2026

Routine microaxial left ventricular support during nonemergent high-risk PCI: an updated systematic review and meta-analysis with Bayesian and grade methodologies.

Expert review of medical devices·2026

Modified Hu-lu-ba-wan and its active component trigonelline ameliorate diabetic renal tubular injury via enhancing PACS2-regulated mitochondria-endoplasmic reticulum contacts and mitophagy.

Fitoterapia·2026

Electrophysiological Remodeling in Chronic Mitral Regurgitation: Underlying Substrates for Atrial Fibrillation.

The Journal of thoracic and cardiovascular surgery·2026

Related Experiment Videos

Effect of alpha-difluoromethylornithine on cardiac polyamine content and hypertrophy

Related Concept Videos

A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome.

New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome.

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide.

Polyamines and neoplastic growth.

Polyamine depletion inhibits etoposide-induced NF-kappaB activation in transformed mouse fibroblasts.

Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth.

Graft IL-33/ST2 signaling promotes cardiac allograft vasculopathy by modulating cardiac resident cell function.

Mitofusin 2 deficiency causes atrial lipid accumulation in experimental and human atrial fibrillation and diabetes mellitus.

PP2A promotes myocardial regeneration through YAP.

Pharmacological modulation of GLI signaling promotes human iPSC-derived cardiomyocyte maturation via PGC1α-associated mitochondrial programs.

Whole-genome sequencing identifies a c.1282C > T missense variant in Taurine Transporter (TauT) associated with taurine-mediated dilated cardiomyopathy in a family of domestic shorthair cats.

Icosapent ethyl activates GPR120 to improve post-myocardial infarction cardiac remodeling by suppressing CXCR3+ inflammatory cells.

Enzyme replacement therapy (ERT) combined with transient low-dose methotrexate (TLD-MTX) results in age- and disease-dependent immune profile changes in Infantile- vs. late-onset Pompe disease patients.

Mitochondria-Targeted Nanozyme Reprograms Dendritic-Cell Immunometabolism via Microenvironment-Responsive CO Release to Treat Periodontitis.

Microaneurysm segmentation in early diabetic retinopathy: a localized patch-based U-Net approach to overcome microscopic lesion oversight.

Routine microaxial left ventricular support during nonemergent high-risk PCI: an updated systematic review and meta-analysis with Bayesian and grade methodologies.

Modified Hu-lu-ba-wan and its active component trigonelline ameliorate diabetic renal tubular injury via enhancing PACS2-regulated mitochondria-endoplasmic reticulum contacts and mitophagy.

Electrophysiological Remodeling in Chronic Mitral Regurgitation: Underlying Substrates for Atrial Fibrillation.

Related Experiment Videos

Effect of alpha-difluoromethylornithine on cardiac polyamine content and hypertrophy

Related Concept Videos

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