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The NMR blood flowmeter--applications.

S X Salles-Cunha, R E Halbach, J H Battocletti

    Medical Physics
    |July 1, 1981
    PubMed
    Summary
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    Nuclear Magnetic Resonance (NMR) blood flow measurement is noninvasive and works through clothing. This study details calibration and application of NMR flowmeters for various forearm conditions and individual artery analysis.

    Area of Science:

    • Biomedical Engineering
    • Medical Imaging
    • Physiology

    Background:

    • Noninvasive blood flow measurement is crucial for diagnosing vascular conditions.
    • Existing methods may be limited by clothing, bandages, or casts.
    • Nuclear Magnetic Resonance (NMR) offers a promising noninvasive approach.

    Purpose of the Study:

    • To describe calibration procedures for NMR blood flowmeters.
    • To report blood flow measurements in various physiological and pathological conditions.
    • To demonstrate techniques for isolating flow signals from individual arteries and specific depths.

    Main Methods:

    • Utilized cylindrical and flat crossed-coil NMR blood flowmeters.
    • Developed and applied two calibration methods for pulsatile and non-pulsatile flows.

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  • Employed flow scanning and ranging techniques for signal separation and depth localization.

    • Main Results:

    • Successfully measured blood flow in the human forearm noninvasively.
    • Demonstrated accurate flow measurements in normal limbs and those with arterial obstructions or fistulas.
    • Showcased the ability to differentiate flow signals from individual arteries (ulnar, radial, brachial) and at specific depths.

    Conclusions:

    • NMR blood flowmetry is a versatile, noninvasive technique applicable to diverse clinical scenarios.
    • The described calibration and signal processing techniques enhance the accuracy and specificity of NMR flow measurements.
    • NMR flowmetry holds significant potential for vascular diagnostics and research.