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Urticaria, vasculitis, hypocomplementemia, and immune-complex glomerulonephritis.

A V Moorthy, D Pringle

Archives of Pathology & Laboratory Medicine

|February 1, 1982

Summary

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Recurrent urticaria with cutaneous vasculitis is a rare immune disorder. This case highlights its association with hypocomplementemia, immune complexes, arthritis, and kidney disease.

Area of Science:

Immunology
Rheumatology
Nephrology

Background:

Recurrent urticaria with cutaneous vasculitis is a systemic immune disorder with an unknown etiology.
This condition presents as hives and skin inflammation, often indicating underlying systemic involvement.

Observation:

A 33-year-old woman presented with recurrent urticaria and cutaneous vasculitis.
The patient exhibited additional symptoms including hypocomplementemia, circulating immune complexes, and arthritis.

Findings:

The patient was diagnosed with immune-complex glomerulonephritis, indicating kidney involvement.
The constellation of symptoms suggests a complex autoimmune process.

Implications:

This case underscores the importance of investigating systemic involvement in patients with recurrent urticaria and cutaneous vasculitis.

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Further research into the pathogenesis of this syndrome is warranted to improve diagnostic and therapeutic strategies.