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Related Concept Videos

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...

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Related Experiment Video

Updated: Jul 28, 2026

Labeling of Single Cells in the Central Nervous System of Drosophila melanogaster
10:33

Labeling of Single Cells in the Central Nervous System of Drosophila melanogaster

Published on: March 4, 2013

From grasshopper to Drosophila: a common plan for neuronal development.

J B Thomas, M J Bastiani, M Bate

    Nature
    |July 19, 1984
    PubMed
    Summary

    The early Drosophila embryo mirrors the grasshopper embryo

    Area of Science:

    • Developmental biology
    • Neuroscience
    • Genetics

    Background:

    • Neuronal specificity mechanisms during development are poorly understood.
    • Grasshopper embryos are ideal for cellular analysis of neuronal development.
    • Drosophila embryos offer advantages for molecular genetic analysis.

    Purpose of the Study:

    • To investigate neuronal development mechanisms in Drosophila.
    • To compare Drosophila and grasshopper embryonic neurodevelopment.
    • To enable combined cellular and molecular genetic studies in Drosophila.

    Main Methods:

    • Comparative analysis of identified neurons.
    • Observation of growth cone behavior.
    • Assessment of selective fasciculation choices.

    More Related Videos

    Dissection and Immunofluorescent Staining of Mushroom Body and Photoreceptor Neurons in Adult Drosophila melanogaster Brains
    10:13

    Dissection and Immunofluorescent Staining of Mushroom Body and Photoreceptor Neurons in Adult Drosophila melanogaster Brains

    Published on: November 6, 2017

    Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices
    04:17

    Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

    Published on: March 8, 2024

    Related Experiment Videos

    Last Updated: Jul 28, 2026

    Labeling of Single Cells in the Central Nervous System of Drosophila melanogaster
    10:33

    Labeling of Single Cells in the Central Nervous System of Drosophila melanogaster

    Published on: March 4, 2013

    Dissection and Immunofluorescent Staining of Mushroom Body and Photoreceptor Neurons in Adult Drosophila melanogaster Brains
    10:13

    Dissection and Immunofluorescent Staining of Mushroom Body and Photoreceptor Neurons in Adult Drosophila melanogaster Brains

    Published on: November 6, 2017

    Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices
    04:17

    Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

    Published on: March 8, 2024

    Main Results:

    • The early Drosophila embryo is a miniature replica of the grasshopper embryo.
    • Identified neurons, growth cones, and fasciculation choices are conserved.
    • Drosophila serves as a model for studying neuronal development.

    Conclusions:

    • Drosophila provides a powerful system for combined cellular and molecular genetic analysis of neuronal development.
    • Cell recognition mechanisms in neuronal development can be studied in Drosophila.
    • This research bridges cellular and genetic approaches to neurodevelopment.