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Related Experiment Videos

Prolonged bleeding time associated with moxalactam administration.

L Fishman, W R Marsh

    Neurosurgery
    |June 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Moxalactam can cause bleeding problems by affecting platelet aggregation, not vitamin K clotting factors. Routine preoperative bleeding time tests are recommended for patients on moxalactam.

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    Area of Science:

    • Pharmacology
    • Hematology

    Background:

    • Moxalactam is a broad-spectrum antibiotic.
    • Coagulopathy is a condition affecting blood clotting.

    Observation:

    • A patient developed coagulopathy while being treated with moxalactam.

    Findings:

    • The coagulopathy was attributed to an effect on platelet aggregation.
    • Moxalactam did not appear to inhibit vitamin K-dependent clotting factors.

    Implications:

    • Preoperative bleeding time assessment is crucial for patients receiving moxalactam.
    • Understanding moxalactam's mechanism of coagulopathy aids in patient management.