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Continuous-cycling peritoneal dialysis for children: an alternative to hemodialysis treatment
Insights
Home continuous-cycling peritoneal dialysis (CCPD) offers effective treatment for children with end-stage renal failure, providing adequate biochemical control and comparable growth rates to hemodialysis.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- End-stage renal failure in children necessitates invasive and prolonged treatment.
- Kidney transplantation is ideal but often unavailable, requiring dialysis until a donor is found.
Purpose of the Study:
- To evaluate home continuous-cycling peritoneal dialysis (CCPD) as an alternative to in-center hemodialysis for pediatric patients.
- To assess the efficacy and complications of CCPD in children with end-stage renal failure.
Main Methods:
- Children with end-stage renal failure were treated with home CCPD.
- Biochemical control, growth rates, and complications were monitored.
Main Results:
- CCPD achieved adequate biochemical control of the uremic state.
- Peritonitis occurred at an average of one episode per 12 patient-months.
- Growth rates on CCPD were equivalent to those on hemodialysis.
Conclusions:
- Home CCPD is a viable alternative to in-center hemodialysis for children.
- CCPD offers the advantage of evening exchanges with minimized parental intervention.
Abstract:
Treatment of end-stage renal failure in children is invasive and prolonged. Although kidney transplantation is often the desired therapy, children usually require some form of life-sustaining dialysis until a suitable donor is found. Home continuous-cycling peritoneal dialysis (CCPD) is a useful alternative to in-center hemodialysis for these children. Adequate biochemical control of the uremic state can be achieved with continuous-cycling peritoneal dialysis. Peritonitis remains the major complication of this form of dialysis, averaging approximately one episode per 12 patient-months. Growth rates of children maintained on continuous-cycling peritoneal dialysis appear to be equivalent to growth rates of children treated with hemodialysis. The advantage of continuous-cycling peritoneal dialysis lies in the fact that exchanges occur during the evening hours and parental intervention is minimized.