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Related Experiment Videos

CT-guided liver biopsies: eight years' experience. Work in progress.

C R Martino, J R Haaga, P J Bryan

    Radiology
    |September 1, 1984
    PubMed
    Summary

    CT-guided liver biopsies using cutting needles yielded significantly more diagnostic tissue than aspiration biopsies. This method offers a higher diagnostic yield for liver abnormalities without substantially increasing complication risks.

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    Area of Science:

    • Radiology
    • Pathology
    • Interventional Radiology

    Background:

    • Liver abnormalities detected via computed tomography (CT) often require tissue diagnosis.
    • CT-guided biopsy is a common procedure for obtaining liver tissue.
    • Different needle types and techniques exist for liver biopsy, each with varying efficacy and risk.

    Purpose of the Study:

    • To compare the diagnostic yield and complication rates of cutting needle biopsies versus aspiration biopsies for CT-guided liver biopsies.
    • To evaluate the correlation of cytologic and pathologic findings with surgical, autopsy, and clinical follow-up.
    • To discuss biopsy techniques, associated risks, and indications.

    Main Methods:

    • 180 patients with CT-demonstrated liver abnormalities underwent CT-guided biopsies.

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  • Procedures utilized 22-gauge Madayag, 14-gauge Travenol, or 18-gauge Menghini needles, singly or in combination.
  • Cytologic, pathologic, and complication data were collected and correlated with follow-up.

    • Main Results:

    • Cutting needle biopsies achieved a diagnostic yield of 89.9%, compared to 65% for aspiration biopsies.
    • Complication rates were 1.44% for cutting needles and 0.83% for aspiration needles.
    • Results were correlated with subsequent surgical, autopsy, and clinical follow-up data.

    Conclusions:

    • Cutting needle biopsies are superior to aspiration biopsies for CT-guided liver tissue acquisition due to higher diagnostic yield.
    • The increased diagnostic yield does not significantly elevate complication risks.
    • CT-guided cutting needle biopsy is an effective method for diagnosing liver abnormalities.