Related Experiment Video
Updated: Aug 18, 2026

09:56
Determination of Mitochondrial Membrane Potential and Reactive Oxygen Species in Live Rat Cortical Neurons
Published on: May 23, 2011
Effect of transition metal ions on lipid peroxidation of rabbit renal cortical mitochondria
Abstract:
Effect of transition metal ions on lipid peroxidation in rabbit renal cortical mitochondria was studied. The lipid peroxidation of mitochondria was promoted by the metal ions tested in the following order of intensity; Fe2+, Hg2+ and Cu2+. Sodium selenite inhibited Fe2+ or Hg2+-induced lipid peroxidation, but it had no influence on the lipid peroxidation stimulated by Cu2+. This result suggests that the mechanism of the stimulatory effect on lipid peroxidation of Cu2+ may be different from that of Fe2+ or Hg2+ in mitochondria.

