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[Preliminary study of HLA markers in French Catalonia]
Forty-two sets of parents and their two children, who had their origins for at least three generations in French Catalonia, were studied for HLA-A,B,C,DR and Bf alleles of the Properdine complement factors. Four haplotypes were observed to be in strong linkage disequilibrium (p less than 10(-3)): A1, Cw7, B8, DR3; Aw30 (Cw5), B18, BfF1, DR3; A1 (Cw6), B17; A29 or Aw23, Cw4, B12, BfF, DR7. The observed linkage disequilibria of these haplotypes in the French Catalonian population were compared with those already described among populations from the Basque country, the Toulouse area and Spanish Catalonia.
Forty-two sets of parents and their two children, who had their origins for at least three generations in French Catalonia, were studied for HLA-A,B,C,DR and Bf alleles of the Properdine complement factors. Four haplotypes were observed to be in strong linkage disequilibrium (p less than 10(-3)): A1, Cw7, B8, DR3; Aw30 (Cw5), B18, BfF1, DR3; A1 (Cw6), B17; A29 or Aw23, Cw4, B12, BfF, DR7. The observed linkage disequilibria of these haplotypes in the French Catalonian population were compared with those already described among populations from the Basque country, the Toulouse area and Spanish Catalonia.