[Duodenal peptic ulcer--hereditary and gastric secretion]

The effect of hereditary predisposition on gastric secretion and acidity in duodenal ulcer was studied. A total of 231 patients (146 males and 85 females) were studied under the conditions of maximum stimulation with pentagastrin. The results reveal that the hereditary tainted probands have higher values of the single indices, with 1,30 to 2,03 times on the average for gastric secretion nd acidity than the patients, not hereditary tainted. The comprehensive analysis of the data obtained show that the sex differences in the degree of the indices studied are, most likely, secondary and seemed to be determined by the higher incidence of the disease among the males, hereditary tainted. That presumption is confirmed also by the fact that no differences in gastric secretion and acidity were established between the males and females with duodenal ulcer non-hereditary tainted.