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Neurourodynamic evaluation of voiding dysfunction in multiple sclerosis.

T Petersen, E Pedersen

    Acta Neurologica Scandinavica
    |June 1, 1984
    PubMed
    Summary
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    Multiple Sclerosis (MS) patients often experience bladder dysfunction, with detrusor hyperreflexia being common. Urge incontinence is the primary symptom, though treatment options and outcomes vary.

    Area of Science:

    • Neurology
    • Urology
    • Neuroscience

    Background:

    • Multiple Sclerosis (MS) frequently causes significant neurological deficits.
    • Voiding dysfunction is a common and distressing symptom in MS patients.
    • Neurourodynamic investigation is crucial for understanding bladder issues in MS.

    Purpose of the Study:

    • To investigate the neurourodynamic findings in patients with definite Multiple Sclerosis presenting with voiding dysfunction.
    • To correlate symptoms with cystometric findings and analyze the types of detrusor dysfunction.
    • To evaluate the impact of detrusor-sphincter dyssynergia on bladder emptying and upper urinary tract complications.

    Main Methods:

    • Neurourodynamic assessment including cystometry and sphincter electromyography (EMG).

    Related Experiment Videos

  • Classification of detrusor hyperreflexia and detrusor-sphincter dyssynergia.
  • Analysis of voiding symptoms, urodynamic parameters, and complications.

    • Main Results:

    • Detrusor hyperreflexia was observed in 73 out of 88 investigated MS patients.
    • Urge incontinence was the predominant symptom; no clear correlation between symptoms and cystometric groups.
    • Detrusor-sphincter dyssynergia was present in 36 patients, impacting bladder emptying differently across subtypes.

    Conclusions:

    • Voiding dysfunction in MS is frequently characterized by detrusor hyperreflexia and urge incontinence.
    • Detrusor-sphincter dyssynergia presents a challenge to effective bladder emptying in some MS patients.
    • Despite significant bladder dysfunction, upper urinary tract complications were infrequent in this cohort.