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Toxic effect of scopolamine eye drops in children
Acta Ophthalmologica
|June 1, 1984
Insights
Acute psychotic reactions in children were observed after using Scopolamine eye drops. Symptoms resolved within 24 hours, suggesting careful patient counseling and alternative medication options like Cyclopentolate.
Area of Science:
- Ophthalmology
- Pediatric Psychiatry
- Clinical Toxicology
Background:
- Scopolamine eye drops are utilized for specific ophthalmic procedures.
- Understanding potential adverse effects in pediatric populations is crucial for safe clinical practice.
Observation:
- Five pediatric cases presented with acute psychotic reactions following the application of 0.2% Scopolamine eye drops.
- Predominant symptoms included visual hallucinations, unusual behavior, and significant restlessness.
- One case also exhibited peripheral symptoms.
Findings:
- All five children experienced complete recovery within 24 hours.
- The observed psychotic reactions were transient and fully reversible.
Implications:
- Healthcare providers should counsel patients and guardians about the potential neuropsychiatric adverse effects of Scopolamine eye drops.
- Consideration of alternative anticholinergic agents, such as Cyclopentolate, may be warranted to minimize these risks.
- Further research into the pediatric neurotoxicity of topical anticholinergics is recommended.
Abstract:
Five children, admitted with acute psychotic reactions after use of Scopolamine eye drops 0.2%, are presented. The predominant symptoms were visual hallucinations, strange behaviour, and restlessness. In one case peripheral symptoms were observed. Recovery was complete in 24 h. Prescription of Scopolamine eye drops should be followed by information of possible adverse effects. Cyclopentolate might be used instead.