Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acetaminophen overdose with fetal demise.

H Haibach, J E Akhter, M S Muscato

    American Journal of Clinical Pathology
    |August 1, 1984
    PubMed
    Summary

    This case study reports the first instance of fetal demise following maternal acetaminophen overdose, with the mother making a full recovery. Fetal liver and maternal serum levels confirmed acetaminophen toxicity as the cause of death.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Horse-related injury patterns: a single center report.

    Journal of orthopaedic surgery and research·2023
    Same author

    Navigated iliac screw placement may reduce radiation and OR time in lumbopelvic fixation of unstable complex sacral fractures.

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2021
    Same author

    Outcome of periprosthetic femoral fractures following total hip replacement treated with polyaxial locking plate.

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2016
    Same author

    Clinical outcome of interprosthetic femoral fractures treated with polyaxial locking plates.

    Injury·2016
    Same author

    Acute hyperhydration reduces athlete biological passport OFF-hr score.

    Scandinavian journal of medicine & science in sports·2015
    Same author

    [Unilateral triangular lumbopelvic stabilization: indications and techniques].

    Der Unfallchirurg·2013

    Area of Science:

    • Toxicology
    • Maternal-Fetal Medicine
    • Critical Care Medicine

    Background:

    • Acetaminophen overdose is a common cause of acute liver injury.
    • Fetal demise can occur in severe maternal poisoning cases.
    • Disseminated intravascular coagulation (DIC) is a potential complication of severe liver disease.

    Observation:

    • A pregnant patient presented with a severe acetaminophen overdose.
    • The overdose resulted in fetal demise.
    • The mother developed disseminated intravascular coagulation (DIC).

    Findings:

    • Fetal liver and maternal serum acetaminophen concentrations confirmed overdose as the cause of fetal death.
    • Maternal DIC was potentially linked to acetaminophen-induced liver disease, the dead fetus, or both.
    • The mother recovered fully despite the severe complications.

    Implications:

    • This case highlights the critical risk of acetaminophen overdose to the fetus.
    • It underscores the importance of prompt management of acetaminophen toxicity in pregnancy.
    • Understanding the pathophysiology of DIC in this context is crucial for maternal care.

    Related Experiment Videos