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[Rhythmic slow wave observed on nocturnal sleep encephalogram in children with idiopathic nocturnal enuresis]
Insights
Children with nocturnal enuresis exhibit specific rhythmic slow wave (RSW) patterns during sleep. These RSW patterns are more frequent in enuretic children and decrease with age, but this decrease is delayed in enuresis cases.
Area of Science:
- Neurophysiology
- Sleep Medicine
- Pediatrics
Context:
- Idiopathic nocturnal enuresis is a common childhood condition with complex etiology.
- Understanding the relationship between sleep patterns and enuresis is crucial for effective management.
- Previous research has not fully elucidated the specific electrophysiological characteristics during sleep in enuretic individuals.
Purpose:
- To investigate the characteristics of rhythmic slow wave (RSW) activity during sleep in children with idiopathic nocturnal enuresis.
- To compare RSW patterns between enuretic children and healthy controls.
- To explore the association between RSW occurrence, sleep stages, age, and stimuli.
Summary:
- Polysomnography revealed no significant differences in sleep stage distribution between enuretic and control groups.
- Nocturnal enuresis occurred across various sleep stages, with a notable prevalence in the second and third sleep cycles.
- Distinct RSW patterns (6-7 Hz in NREM, 3-5 Hz in REM sleep) were observed during enuretic episodes.
- RSW incidence was higher in enuretic children, decreased with age, but showed a delayed decline in enuresis.
- RSW was reactively provoked by sleep stage shifts and movements, with concurrent inhibition of heart rate and respiratory changes.
Impact:
- Identifies specific electrophysiological markers (RSW) associated with nocturnal enuresis.
- Suggests a potential role for RSW abnormalities in the pathophysiology of enuresis.
- Provides insights for developing targeted interventions for enuresis based on sleep physiology.
Abstract:
Whole-night sleep polygraph by removing the first-night effect was recorded for 15 cases of idiopathic nocturnal enuresis and 10 cases of normal control, thereby, review was made on the relation between sleep and etiology of nocturnal enuresis as well as the appearing characteristics of rhythmic slow wave. (hereinafter referred to R.S.W.). Thus the following results were obtained. Both groups of nocturnal enuresis and normal control showed no significant difference under the same experimental conditions for the rate of encephalogramic sleep stage. Nocturnal enuresis was observed in nearly the same number of cases at any stage of sleep except Stage 1 (hereinafter referred to as S), and there were many cases in the second and third sleep cycles. At the time of occurrence of nocturnal enuresis, 6-7 Hz R.S.W. continued as long as 15-40 seconds in NREM-sleep. Also, 3-5 Hz R.S.W. was observed in REM sleep. R.S.W. was observed even in normal cases, while its incidence was high in the cases of nocturnal enuresis, and the decrease was observed with advancement of age, however, the decrease was delayed in the cases of nocturnal enuresis. R.S.W. was provoked reactively against the stimuli such as the change in the electro-encephalogramic sleep stage and body movements. On the other hand, there was an inhibitory tendency of the changes in heart rate and respiration during the appearance of R.S.W. By the above result and the resemblance between R.S.W. and DR theta, R.S.W.(ABSTRACT TRUNCATED AT 250 WORDS)