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Related Experiment Videos

Biocompatible ossicular implants.

J J Shea, J R Emmett

    Archives of Otolaryngology (Chicago, Ill. : 1960)
    |April 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Proplast and Plastipore prostheses effectively restore hearing in tympanoplasty surgeries. These biocompatible materials promote tissue ingrowth, leading to significant air conduction gain and closure of the air-bone gap.

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    Area of Science:

    • Otolaryngology
    • Biomaterials Science
    • Regenerative Medicine

    Background:

    • Tympanoplasty aims to reconstruct the middle ear and restore hearing.
    • Biocompatible implant materials that promote tissue ingrowth are crucial for successful ossicular reconstruction.
    • Proplast and Plastipore are novel biocompatible materials designed for enhanced tissue integration in implantable devices.

    Purpose of the Study:

    • To evaluate the efficacy of Proplast and Plastipore prostheses in tympanoplasty procedures.
    • To assess the hearing outcomes, specifically air conduction gain and air-bone gap closure, using these materials.
    • To determine the long-term success rates and complication profile of Proplast and Plastipore in ossicular reconstruction.

    Main Methods:

    • A retrospective study involving 225 tympanoplasty procedures utilizing Proplast and Plastipore prostheses.

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  • Prostheses included total ossicular replacement prostheses (TORP) and partial ossicular replacement prostheses (PORP).
  • Hearing outcomes were assessed over a 12 to 28-month follow-up period, measuring air conduction gain and air-bone gap closure.

    • Main Results:

    • Total ossicular replacement prosthesis (TORP) in tympanoplasty (133 cases) yielded an average air conduction gain of 19 dB with 65% air-bone gap closure to within 20 dB.
    • Partial ossicular replacement prosthesis (PORP) in tympanoplasty (17 cases) showed an average air conduction gain of 20 dB and 100% air-bone gap closure.
    • TORP in tympanoplasty/mastoidectomy (53 cases) resulted in 19 dB average air conduction gain and 87% air-bone gap closure.
    • PORP in tympanoplasty/mastoidectomy (22 cases) achieved a 25 dB average air conduction gain and 100% air-bone gap closure.
    • A low extrusion rate of 2.2% (5 out of 225 prostheses) was observed for Plastipore.

    Conclusions:

    • Proplast and Plastipore are effective biocompatible materials for ossicular reconstruction in tympanoplasty.
    • Both TORP and PORP configurations demonstrate significant improvements in hearing outcomes.
    • The materials offer high rates of air-bone gap closure and a low complication rate, supporting their use in middle ear surgery.