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Late response in exercise-induced asthma.

C R Horn, R M Jones, D Lee

    Clinical Allergy
    |July 1, 1984
    PubMed
    Summary
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    Exercise can trigger asthma symptoms, including a delayed response hours later. This study confirms a late-phase reaction in exercise-induced asthma, challenging previous beliefs.

    Area of Science:

    • Pulmonology
    • Exercise Physiology
    • Allergy and Immunology

    Background:

    • Exercise-induced asthma is a common condition.
    • The existence of a late-phase response to exercise in asthma has been debated.

    Purpose of the Study:

    • To investigate the presence and significance of a late-phase response in exercise-induced asthma.

    Main Methods:

    • Eight subjects with exercise-induced bronchospasm were monitored.
    • Pulmonary function tests, including FEV1, were measured over time post-exercise.
    • Subjects were categorized based on early and late responses.

    Main Results:

    • Four out of eight subjects exhibited a late response 5-6 hours after exercise.

    Related Experiment Videos

  • A statistically significant difference in FEV1 was observed between subjects with and without a late response at 5-6 hours.
  • The late response was not universally present in all subjects studied.

    • Conclusions:

    • The study provides evidence for a late-phase response in exercise-induced asthma.
    • This finding challenges the notion that a late response does not occur in exercise-induced asthma.
    • Further research may be warranted to understand the mechanisms and prevalence of this late response.