Comparison of iohexol and metrizamide in dynamic CT of the upper abdomen

Contrast enhancement (CE) of the aorta, liver and spleen obtained with non-ionic monomer of contrast media (CM) iohexol and metrizamide, was studied by dynamic computerized tomography in 18 and 14 patients, respectively. Six scans per minute were performed during 2 minutes and then single scans were taken at 3, 4 and 5 minutes after intravenous bolus doses of 18.5 g iodine. The mean CE and the pattern of washout with these two CM were similar in spite of their different molecular structure and physiochemical properties.