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Muscular calcification following injection of vitamin E in newborn infants
European Journal of Pediatrics
|June 1, 1984
Insights
Severe thigh calcifications occurred in three newborns following vitamin E injections. Fortunately, these vitamin E calcifications resolved completely without any lasting clinical effects.
Area of Science:
- Neonatology
- Pediatric Radiology
- Dermatology
Background:
- Intramuscular vitamin E administration is sometimes used in neonates.
- Potential adverse effects of neonatal interventions require careful monitoring.
Observation:
- Three newborn infants developed extensive thigh calcifications.
- Calcifications were noted after receiving intramuscular vitamin E injections.
Findings:
- Severe subcutaneous calcifications in the thigh region were observed.
- The calcifications resolved spontaneously over time.
- No residual clinical abnormalities were detected post-resolution.
Implications:
- This case report highlights a potential, albeit reversible, adverse effect of intramuscular vitamin E in newborns.
- Close monitoring for calcification is warranted in infants receiving this treatment.
- The benign prognosis suggests that conservative management is appropriate.
Abstract:
Three newborn infants are presented in this case report who developed severe calcifications in the thighs after intramuscular injections of vitamin E. The prognosis seems to be good. Calcifications disappeared without clinical residue.