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Bronchospasm induced by vanillin and lactose
Abstract:
Bronchospasm caused by vanillin and lactose was detected in controlled double-blind challenge tests in an asthmatic patient. It is recommended that all flavouring agents and dyes should be removed from drugs. Lactose is not a suitable placebo for challenges in asthmatic patients. A better choice is cellulose, which is not resorbed by man.