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[Hyperprolactinemia in children with celiac disease].

A Várkonyi, G Falkay

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |July 1, 1984
    PubMed
    Summary

    Serum prolactin levels are normal in healthy children and coeliac disease patients on a gluten-free diet. However, significant hyperprolactinemia was observed in children with coeliac disease actively consuming gluten.

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    Area of Science:

    • Endocrinology
    • Gastroenterology
    • Pediatrics

    Context:

    • Coeliac disease is an autoimmune disorder triggered by gluten ingestion.
    • Elevated prolactin levels (hyperprolactinemia) can have various health implications.
    • Understanding the relationship between coeliac disease and hormonal changes is crucial for comprehensive patient care.

    Purpose:

    • To investigate the effect of gluten intake on serum prolactin levels in children with coeliac disease.
    • To compare prolactin levels in coeliac patients on a gluten-free diet versus those consuming gluten.
    • To establish reference prolactin levels in healthy children.

    Summary:

    • Serum prolactin was serially measured in children with coeliac disease (CD) and healthy controls.
    • Coeliac patients consuming gluten exhibited significant hyperprolactinemia.
    • Prolactin levels were normal in healthy children and in coeliac patients adhering to a gluten-free diet.

    Impact:

    • This study highlights a potential hormonal imbalance associated with active coeliac disease in children.
    • Findings suggest that monitoring prolactin may be relevant in managing coeliac disease.
    • Results contribute to understanding the systemic effects of gluten in coeliac disease.

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