Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subsequent monoclonal gammopathies.

S Ottó, M Börzsönyi, S Eckhardt

    Oncology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Endocannabinoid analysis in GlucoEXACT plasma: Method validation and sample handling recommendations.

    Talanta·2024
    Same author

    Metabolomic and lipidomic fingerprints in inflammatory skin diseases - Systemic illumination of atopic dermatitis, hidradenitis suppurativa and plaque psoriasis.

    Clinical immunology (Orlando, Fla.)·2024
    Same author

    Correction to: Comparative Effectiveness and Durability of Biologics in Clinical Practice: Month 12 Outcomes from the International, Observational Psoriasis Study of Health Outcomes (PSoHO).

    Dermatology and therapy·2024
    Same author

    Comparative Effectiveness and Durability of Biologics in Clinical Practice: Month 12 Outcomes from the International, Observational Psoriasis Study of Health Outcomes (PSoHO).

    Dermatology and therapy·2023
    Same author

    A novel calcipotriol and betamethasone dipropionate (CAL/BDP) PAD-cream demonstrates greater improvements in daily activities and personal relationships than CAL/BDP gel/TS: A post-hoc analysis of DLQI outcomes from two phase 3 placebo-controlled randomized clinical trials in mild-to-moderate psoriasis.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2023
    Same author

    Randomized Phase 3 trial demonstrating high efficacy, favourable safety and convenience of a novel calcipotriol and betamethasone dipropionate cream for the treatment of psoriasis.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2023

    This study investigated subsequent monoclonal gammopathies in 21 patients. Researchers explored the development of immunoglobulin-producing clones following non-tumour or tumour conditions.

    Area of Science:

    • Hematology
    • Oncology
    • Immunology

    Background:

    • Monoclonal gammopathies, including multiple myeloma and related disorders, are characterized by the proliferation of a single clone of immunoglobulin-producing plasma cells.
    • The development of these conditions can be influenced by various underlying factors, including pre-existing non-tumour or tumour states.
    • Understanding the sequential development of monoclonal gammopathies is crucial for accurate diagnosis and patient management.

    Purpose of the Study:

    • To investigate the characteristics and development pathways of subsequent monoclonal gammopathies.
    • To analyze the relationship between preceding non-tumour or tumour conditions and the emergence of monoclonal gammopathies.
    • To explore the potential mechanisms involved in the clonal expansion of immunoglobulin-producing cells.

    Related Experiment Videos

    Main Methods:

    • Retrospective analysis of 221 patients producing M protein.
    • Inclusion of 21 cases with subsequent monoclonal gammopathies.
    • Utilized data from case history, autopsy, histology, and immunochemistry during continuous observation.

    Main Results:

    • Identified 21 cases of monoclonal gammopathies developing after initial non-tumour or tumour states.
    • Data analysis provided insights into the temporal relationship between initial conditions and gammopathy development.
    • Immunochemical and histological findings contributed to understanding clonal evolution.

    Conclusions:

    • Subsequent monoclonal gammopathies can arise following various non-tumour and tumour conditions.
    • The study highlights the importance of continuous observation and comprehensive analysis in identifying these sequential disorders.
    • Further research into the specific pathways of immunoglobulin-producing monoclonal cell clone development is warranted.