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Intermittent claudication: factors determining outcome.

W G Hughson, J I Mann, D J Tibbs

    British Medical Journal
    |May 27, 1978
    PubMed
    Summary
    This summary is machine-generated.

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    Stopping smoking significantly improves prognosis for intermittent claudication (IC) patients. This correctable factor is crucial for better outcomes, outweighing other medical risks in managing IC.

    Area of Science:

    • Vascular Medicine
    • Public Health

    Background:

    • Intermittent claudication (IC) is a significant vascular disease with a substantial impact on patient prognosis and healthcare utilization.
    • Understanding the natural history and prognostic factors of IC is crucial for effective patient management and resource allocation.

    Purpose of the Study:

    • To investigate the natural history of intermittent claudication (IC).
    • To identify key factors influencing the outcome of IC patients.
    • To emphasize the importance of smoking cessation in improving IC prognosis.

    Main Methods:

    • Follow-up study of two patient groups (60 and 160 patients) for 4-8 years post-referral or hospital admission for IC.
    • Analysis of prognostic factors including smoking status, age, coronary artery disease, cerebrovascular disease, and diabetes.

    Related Experiment Videos

  • Assessment of patient outcomes, hospital admissions, and life expectancy.

    • Main Results:

    • Patients with IC who stopped or reduced smoking after referral demonstrated a significantly improved prognosis.
    • Factors associated with adverse outcomes included older age, coronary artery disease, cerebrovascular disease, and diabetes.
    • The study population experienced substantial hospital admissions and reduced life expectancy.

    Conclusions:

    • Smoking cessation is a critical, correctable factor that greatly improves the prognosis for intermittent claudication (IC) patients.
    • Encouraging smoking cessation after IC diagnosis is paramount, as it appears more influential than less treatable medical risk factors.
    • IC significantly impacts life expectancy and necessitates comprehensive management strategies.