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Patterns of bacteremia in pediatrics practice: factors affecting mortality rates

C S Bryan, K L Reynolds, C W Derrick

    Pediatric Infectious Disease
    |July 1, 1984
    PubMed

    Insights

    This study analyzed pediatric bacteremia (bloodstream infection) from 1977-1981. Bacteremia mortality was 7.6%, with most deaths in newborns, highlighting the need for neonatal infection control.

    Area of Science:

    • Pediatric Infectious Diseases
    • Clinical Microbiology
    • Epidemiology

    Background:

    • Bacteremia, a bloodstream infection, poses significant risks in pediatric patients.
    • Understanding contemporary patterns and mortality is crucial for effective clinical management.
    • Previous data on pediatric bacteremia patterns and outcomes were limited.

    Purpose of the Study:

    • To analyze episodes of bacteremia in children (birth to 17 years) in a metropolitan area.
    • To determine current patterns of bacteremia and associated mortality.
    • To identify specific sources of bacteremia with zero mortality.

    Main Methods:

    • Retrospective analysis of all bacteremia episodes in pediatric patients.
    • Data collected from major hospitals in one metropolitan area between 1977 and 1981.
    • Mortality specifically attributed to bacteremia was determined using defined criteria.

    Main Results:

    • A total of 713 episodes of bacteremia were analyzed.
    • Overall mortality was 13.6%, with mortality specifically attributed to bacteremia at 7.6%.
    • Neonatal period accounted for the majority of bacteremia-attributed deaths (34/54).

    Conclusions:

    • Pediatric bacteremia mortality is significant, particularly in neonates.
    • Certain common sources like otitis media and skin infections did not contribute to mortality.
    • Age-specific analysis reveals critical risk periods for bacteremia-related mortality in children.

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