Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tuberculosis management in Soweto.

L D Saunders, L M Irwig, T D Wilson

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |September 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Myotube-specific activity of the human aldolase A M-promoter requires an overlapping binding site for NF1 and MEF2 factors in addition to a binding site (M1) for unknown proteins.

    Journal of molecular biology·1995
    Same author

    Glucose, growth hormone, cortisol, and insulin responses to glucagon injection in normal infants, aged 0.5-12 months.

    The Journal of clinical endocrinology and metabolism·1995
    Same author

    Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells.

    Molecular and cellular biology·1995
    Same author

    Functional dissection of the brain-specific rat aldolase C gene promoter in transgenic mice. Essential role of two GC-rich boxes and an HNF3 binding site.

    The Journal of biological chemistry·1995
    Same author

    Gene delivery into the central nervous system by nasal instillation in rats.

    Gene therapy·1995
    Same author

    Reduction in obstructive breathing events during body rocking: a controlled polygraphic study in preterm and full-term infants.

    Pediatrics·1995
    Same journal

    SAMA Health Summit Abstracts.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    Same journal

    On behalf of the South African Medical Association (SAMA), The Scientific Committee of the SAMA Health Summit, is pleased to pesent this abstract issue, showcasing the posters and oral presentations delivered at the Summit, which was held from 22-24 May 2026.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    Same journal

    Proceedings of the 2<sup>nd</sup> Data Driven Surgery Conference (DDSC 2025).

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    Same journal

    Clinical practice guidelines for the management of fever and neutropenia in South African children and adolescents with cancer.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    Same journal

    The changing fortunes of the District Health System in SA (1994 - 2020): A retrospective review.

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    Same journal

    Thomas Micheal Guntram Ignaz Rehle (1951 - 2025).

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
    See all related articles

    Tuberculosis (TB) treatment adherence is low in Soweto, South Africa, with only 28% of patients receiving adequate therapy. However, investigating home contacts of TB patients is effective for case finding.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Epidemiology

    Background:

    • Tuberculosis (TB) remains a significant public health challenge in South Africa, even in urban areas with developed health services.
    • Effective chemotherapy is available, yet challenges in TB management persist in Soweto.

    Purpose of the Study:

    • To assess the adequacy of TB treatment among known patients in Soweto.
    • To evaluate the effectiveness of investigating home contacts for TB case finding.

    Main Methods:

    • Retrospective analysis of TB patient treatment records and clinic attendance in Soweto.
    • Assessment of home contact investigation rates and subsequent TB notification.

    Main Results:

    • Only 28% of newly notified TB patients received at least 80% of their required first-year treatment.

    Related Experiment Videos

  • Infrequent clinic attendance led to inadequate dosages, with 17% of patients over 10 years old still having bacilli in sputum after 4 months.
  • Approximately two-thirds of home contacts were investigated, leading to 5% new TB notifications.

    • Conclusions:

    • Significant challenges exist in ensuring adequate TB treatment completion and dosage in Soweto.
    • Home-contact tracing is a valuable strategy for identifying new TB cases and should be continued.