[Information content of endogenous creatinine parameters for kidney function diagnosis in glomerulonephropathies]

The functional-diagnostic findings, namely serum creatinine level, 24-h creatinine clearance, 1-h (morning) creatinine clearance and inulin clearance, of 58 glomerulo-nephropathy patients were evaluated using regression and correlation analysis. For clinical nephrology it is recommended not to measure 24-h creatinine clearance. For the purpose of diagnosing kidney function the information content of the serum creatinine level is sufficient if the hyperbolic relation to the GFR is taken into account. For clinical-scientific nephrology standardized short-term creatinine estimation in combination with direct or indirect GFR measurement (and other parameters of kidney function) is advisable.