Recurrences of acute posterior multifocal placoid pigment epitheliopathy

Acute posterior multifocal placoid pigment epitheliopathy recurred in seven patients (all men, ranging in age from 25 to 43 years). In all seven cases swelling of the pigment epithelium resolved rapidly but left a permanent pigmentary disturbance. Loss of choriocapillaris occurred in six cases. Three patients had severe unilateral visual loss. Three patients had used antimicrobial drugs (two of them repeatedly), suggesting that in some cases this condition may be a manifestation of a hypersensitivity reaction to the antimicrobial agent.