[Thrombogenic thrombopenia induced by heparin]

Three cases of heparin induced thrombotic thrombocytopenia are reported. Pathogenesis, clinical and biological manifestations as well as treatment are reviewed. Treatment consisted in replacing the heparin by a vitamin K antagonist or a low molecular weight heparin. During heparin treatment, the risk of thrombotic thrombocytopenia should be kept in mind and the platelet count monitored from time to time.