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Related Experiment Videos

Vitamin B12 absorption after necrotizing enterocolitis.

J E Collins, C J Rolles, H Sutton

    Archives of Disease in Childhood
    |August 1, 1984
    PubMed
    Summary
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    Neonatal surgery for necrotizing enterocolitis can impair vitamin B12 absorption. Routine monitoring for vitamin B12 deficiency is recommended for at-risk infants following ileum resection.

    Area of Science:

    • Neonatal surgery
    • Gastroenterology
    • Nutritional science

    Background:

    • Necrotizing enterocolitis (NEC) is a serious condition in premature infants.
    • Surgical resection of the terminal ileum is a common treatment for NEC.
    • Ileum resection can lead to malabsorption of vitamin B12.

    Purpose of the Study:

    • To describe a method for measuring vitamin B12 absorption in neonates.
    • To assess the risk of vitamin B12 malabsorption and deficiency after ileum resection.
    • To recommend follow-up protocols for affected infants.

    Main Methods:

    • A specific method was employed to measure vitamin B12 absorption.
    • Results from this measurement method were collected and analyzed.

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    Main Results:

    • The study successfully measured vitamin B12 absorption in neonates post-ileum resection.
    • Findings indicate a potential risk for malabsorption and subsequent deficiency.

    Conclusions:

    • Infants undergoing terminal ileum resection for NEC are at risk of vitamin B12 malabsorption.
    • Vitamin B12 absorption assessment should be a standard part of follow-up care for these children.