Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Growth hormone levels in psoriasis.

G C Priestley, D J Gawkrodger, J Seth

    Archives of Dermatological Research
    |January 1, 1984
    PubMed
    Summary

    Plasma growth hormone levels were studied in patients with psoriasis and eczema. While some individuals showed high levels, these were not statistically significant and may be a secondary effect of skin disease, not its cause.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Skin and respiratory ill-health attributed to occupational face mask use.

    Occupational medicine (Oxford, England)·2022
    Same author

    Integrating neuronal involvement into the immune and genetic paradigm of vitiligo.

    Clinical and experimental dermatology·2020
    Same author

    Skin disease case mix in the early 1920s: diagnoses prevalent at the time of the founding of the British Association of Dermatologists.

    The British journal of dermatology·2020
    Same author

    British Association of Dermatologists centenary year: standing on the shoulders of giants.

    The British journal of dermatology·2020
    Same author

    Once weekly targeted excimer light produced modest repigmentation of vitiligo over a 20-week period.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2018
    Same author

    Ambient humidity and the skin: the impact of air humidity in healthy and diseased states.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2016

    Area of Science:

    • Endocrinology
    • Dermatology
    • Metabolic disorders

    Background:

    • Psoriasis and eczema are common inflammatory skin conditions.
    • Growth hormone (GH) plays a role in metabolism and cell growth.
    • The relationship between GH levels and these skin diseases is not well understood.

    Purpose of the Study:

    • To investigate plasma growth hormone levels in patients with psoriasis and eczema.
    • To determine if elevated GH is associated with the pathogenesis of psoriasis.

    Main Methods:

    • Fasting plasma samples were collected from 12 patients with psoriasis, 5 with eczema, and 6 healthy controls.
    • Plasma growth hormone levels were measured using a standard assay.
    • Statistical analysis was performed to compare GH levels between groups.

    Main Results:

    • Mean plasma GH levels were higher in psoriatic patients (4.4 +/- 1.4 mU/l) compared to eczema patients (2.7 +/- 1.7 mU/l) and normal subjects (1.2 +/- 0.3 mU/l).
    • These differences were not statistically significant.
    • Exceptionally high GH levels were observed in five psoriasis patients and one eczema patient.
    • Leaner psoriatic patients tended to have higher GH levels.

    Conclusions:

    • Raised plasma growth hormone is unlikely to be the primary cause of psoriasis.
    • Elevated GH levels may be a secondary effect of the skin disease in some individuals.
    • Further research is needed to elucidate the role of GH in inflammatory skin conditions.

    Related Experiment Videos